Authors:Mark Ptashne, Alexander Gann,
Publisher: Cold Spring Harbor Laboratory Press
Keywords: signals, amp, genes
Number of Pages: 192
Published: 2001-11-13
List price: $59.00
ISBN-10: 0879696311
ISBN-13: 9780879696313

Genes & Signals analyzes gene regulation from a new perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others. A general theme emerges, one that proposes how a rather restricted set of signals and enzymatic functions has been used in evolution to generate complex life forms of different types.

Author: Elliot M. Meyerowitz
Publisher: Cold Spring Harbor Laboratory Press
Keywords: monograph, arabidopsis
Number of Pages: 1270
Published: 1994-12
List price: $88.00
ISBN-10: 0879694289
ISBN-13: 9780879694289

The cruciferous weed Arabidopsis thialiana has become a model system for the study of an unusually wide variety of aspects of plant biology. As a result, nearly all aspects of Arabidopsis biology are now under investigation, more scientists are involved, and plant science as a whole has been invigorated. This book is the first comprehensive account of what is known about the organism. The information is presented in the context of plant biology in general, with the properties of Arabidopsis mutants and the insights derived from their analysis as a unifying theme. The book’s scope incl

Authors:Gregory J. Hannon, Gregory J. Hannon,
Publisher: Cold Spring Harbor Laboratory Press
Keywords: manual, silencing, gene, guide, rnai
Number of Pages: 436
Published: 2003-09-01
List price: $130.00
ISBN-10: 0879696419
ISBN-13: 9780879696412

The ability of double stranded RNA to inhibit the expression of genes with an appropriate sequence can be harnessed to silence target genes in vitro in a new and powerful way. This volume combines reliable RNAi protocols for a variety of species with discussion of strategies for the effective design of experiments using this important new technique that is changing the way experimental science is done.

Author: Errol C. Friedberg
Publisher: Cold Spring Harbor Laboratory Press
Keywords: watson, james, life, writing
Number of Pages: 193
Published: 2004-09
List price: $26.00
ISBN-10: 0879697008
ISBN-13: 9780879697006

James Watson’s fame as a scientist and research leader overshadows his considerable achievements as an innovator in the form and style of scientific communication. This book surveys Watson’s books and essays from the perennially best–selling The Double Helix through his classic textbooks of the 1960s and 70s, polemics on ethical questions about genetic technology, to more recent works of autobiography.

Authors:Hillary E. Sussman, Hillary E. Sussman, Maria A. Smi
Publisher: Cold Spring Harbor Laboratory Press
Keywords: monograph, series, harbor, spring, cold, genomes
Number of Pages: 488
Published: 2006-05-01
List price: $59.00
ISBN-10: 0879698071
ISBN-13: 9780879698072

Hundreds of genomes have been completely sequenced in the past decade, significantly advancing our understanding of genome structure and function. Genomes comprises a collection of review articles reprinted from the 10th anniversary of the journal Genome Research that capture the status of genomic research in a selection of model species - from microbes to human. Written by leaders in the field, each chapter focuses on a kingdom, group, or species and offers a unique perspective on the history, the current status, and future of genomics research. Topics addressed include gene regulatory networ

Author: Stewart Scherer
Publisher: Cold Spring Harbor Laboratory Press
Keywords: genome, human, guide, short
Number of Pages: 173
Published: 2008-05-30
List price: $29.00
ISBN-10: 0879697911
ISBN-13: 9780879697914

How many genes are in the human genome? Which genes are commonly associated with genetic diseases? How many mobile elements, simple sequence repeats, or protein kinases are encoded in the genome? What are the largest genes and proteins? How similar are human proteins to those of mouse, yeast, or bacteria? Although the human genome has been sequenced, it often can be surprisingly difficult to find answers to seemingly simple questions about its characteristics. This convenient handbook, written in question-and-answer format, allows researchers and teachers alike access to basic facts about the

Authors:Theodore Friedmann, Theodore Friedmann, John Rossi,
Publisher: Cold Spring Harbor Laboratory Press
Keywords: rna, laboratory, manual, dna, expression, transfer, delivery, gene
Number of Pages: 793
Published: 2006-12-01
List price: $167.00
ISBN-10: 0879697652
ISBN-13: 9780879697655

Understanding GENE FUNCTION and regulation requires rigorous testing in live cells and organisms. Recent advances have provided a variety of new strategies for delivering DNA and RNA into cells and probing their expression, as well as new clinical applications that rely upon the introduction of genetic material. The vast number of available techniques for clinical and laboratory research often makes selecting the optimal method a difficult process. Gene Transfer; Delivery and Expression of DNA and RNA provides the first comprehensive guide to technical approaches for delivering nucleic acids i