Authors:Jacqueline D. Reeves, Jacqueline D. Reeves, Cynthia
Publisher: Birkhäuser Basel
Keywords: therapy, milestones, drug, hiv, inhibitors, entry
Number of Pages: 200
Published: 2007-08-17
List price: $159.00
ISBN-10: 3764377828
ISBN-13: 9783764377823

Entry Inhibitors in HIV Therapy presents the current status of this relatively new and highly dynamic class of inhibitors and provides a unique overview of obstacles and considerations for HIV entry inhibition compared to other antiretroviral targets. The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry

Authors:Harm Bart, Israel Gohberg, Marinus A. Kaashoek, AndrÃ
Publisher: Birkhäuser Basel
Keywords: operator, linear, applications, advances, operators, systems, theory, method, matrix, functions, state, space, factorization
Number of Pages: 409
Published: 2007-12-10
List price: $179.00
ISBN-10: 3764382678
ISBN-13: 9783764382674

The present book deals with factorization problems for matrix and operator functions. The problems originate from, or are motivated by, the theory of non-selfadjoint operators, the theory of matrix polynomials, mathematical systems and control theory, the theory of Riccati equations, inversion of convolution operators, theory of job scheduling in operations research. The book systematically employs a geometric principle of factorization which has its origins in the state space theory of linear input-output systems and in the theory of characteristic operator functions. This principle allows on

Authors:Joseph A. Ball, Joseph A. Ball, Yuli Eidelman, J. Wil
Publisher: Birkhäuser Basel
Keywords: operator, advances, theory, applications, matrix, recent
Number of Pages: 338
Published: 2007-12-20
List price: $209.00
ISBN-10: 3764385383
ISBN-13: 9783764385385

This book expands the lectures given at IWOTA 05 (International Workshop on Operator Theory and Applications) which was held at the University of Connecticut, Storrs, USA, July 24 27, 2005. Many developments on the cutting edge of research in operator theory, matrix theory, coding theory, system theory, control theory and numerical linear algebra are reflected in this collection of original articles. The volume is of a cross-disciplinary nature. A number of papers are devoted to the analysis and algorithms for matrices with quasiseparable structure which is an active area of concurrent res

Authors:Maria Amélia Bastos, Maria Amélia Bastos, Israel G
Publisher: Birkhäuser Basel
Keywords: operator, applications, theory, advances, algebras
Number of Pages: 437
Published: 2008-05-23
List price: $239.00
ISBN-10: 3764386835
ISBN-13: 9783764386832

This book is composed of three survey lecture courses and some twenty invited research papers presented to WOAT 2006 - the International Summer School and Workshop on Operator Algebras, Operator Theory and Applications, which was held at Lisbon in September 2006. The volume reflects recent developments in the area of operator algebras and their interaction with research fields in complex analysis and operator theory. The lecture courses contain: an introduction to two classes of non-selfadjoint operator algebras, the generalized analytic Toeplitz algebras associated with the Fock space of a gr

Authors:Jeffrey M. Weinberg, Jeffrey M. Weinberg,
Publisher: Birkhäuser Basel
Keywords: therapy, drug, milestones, psoriasis, treatment
Number of Pages: 183
Published: 2008-02-06
List price: $169.00
ISBN-10: 3764377224
ISBN-13: 9783764377229

Psoriasis is an inherited skin disease that has been diagnosed in 4.5 million adults in the United States. About 10 percent to 30 percent of people with psoriasis also develop psoriatic arthritis, which causes pain, stiffness and swelling in and around the joints. The book reviews the clinical manifestations of these two entities. The main focus is on the evolving paradigm of therapy. Topical and ultraviolet therapy are discussed first, followed by traditional systemic therapy. A major focus is on biologic therapies. New agents in development are also reviewed. The book concludes with an e

Author: João Caramalho Domingues
Publisher: Birkhäuser Basel
Keywords: historical, studies, networks, science, calculus, lacroix
Number of Pages: 468
Published: 2008-05-23
List price: $169.00
ISBN-10: 3764386371
ISBN-13: 9783764386375

Silvestre François Lacroix (Paris, 1765 - ibid., 1843) was a most influential mathematical book author. His most famous work is the three-volume Traité du calcul différentiel et du calcul intégral (1797-1800; 2nd ed. 1810-1819) an encyclopedic appraisal of 18th-century calculus which remained the standard reference on the subject through much of the 19th century, in spite of Cauchy’s reform of the subject in the 1820’s. Lacroix and the Calculus is the first major study of Lacroix s large Traité. It uses the unique and massive bibliography given by Lacroix to explore

Authors:Frank Petersen, Frank Petersen, René Amstutz,
Publisher: Birkhäuser Basel
Keywords: drug, research, progress, volume, compounds, drugs, natural
Number of Pages: 427
Published: 2008-04-28
List price: $279.00
ISBN-10: 3764385944
ISBN-13: 9783764385941

The use of substances derived from plants, fungi, bacteria and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today’s pharmaceutical market. In molecular biological research, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of invo
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