Author: G. V. Sherbet
Publisher: CRC Press
Keywords: cancer, signalling, calcium
Number of Pages: 384
Published: 2000-11-29
List price: $219.95
ISBN-10: 0849309425
ISBN-13: 9780849309427

Calcium signalling occupies a preeminent position in the signal transduction system of the cell by virtue of its participation in a wide range of physiological functions together with the biological events associated with genetic expression, cell proliferation and apoptosis, as well as cell differentiation and morphogenesis. It is an important feature of cell adhesion and motility; the integrity of the calcium binding proteins themselves is a basic requirement of normal biological function. In fact, the deregulation of calcium signaling is now regarded as the primary event in the pathogenesis,

Author: John Hancock
Publisher: Oxford University Press, USA
Keywords: signalling, cell
Number of Pages: 352
Published: 2010-03-26
List price: $79.95
ISBN-10: 0199232105
ISBN-13: 9780199232109

Signalling within and between cells is an essential part of many biological processes, from the development of the body to the activity of our immune system.Cell Signalling, Third Edition, presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems. Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms before examining ho

Author: Ernst J. M. Helmreich
Publisher: Oxford University Press, USA
Keywords: signalling, cell, biochemistry
Number of Pages: 368
Published: 2001-09-13
List price: $99.00
ISBN-10: 0198508204
ISBN-13: 9780198508205

The Biochemistry of Cell Signalling deals in depth with the principles of cell signalling, concentrating on structure and mechanism. It will serve as a reliable map through the maze of cell signalling pathways and help the reader understand how malfunctions in these pathways can lead to disease. The book is divided into four parts. Part 1 describes the machinery of signal transduction starting with the properties of signals, receptors (including receptor activation), regulators, and the molecules that link receptor and regulator. The design of signalling cascades is explained by describing ce

Author: Dorothy T. Leeds
Publisher: Nova Science Publishers
Keywords: research, signalling, cellular, focus
Number of Pages: 161
Published: 2006-04-18
List price: $210.00
ISBN-10: 1594546193
ISBN-13: 9781594546198

Cell signalling is the communication inside a cell or with its environment. It plays an important role in cellular growth, survival and apoptosis. For instance, the growth of a cell requires production of certain proteins. The genes that encode these proteins are located in DNA inside the nucleus while the initial signal for cellular growth may come from outside the cell. To induce the expression of these genes, the external signal must pass through specific pathways to reach these genes in DNA. The signalling pathway involves several proteins. If any one of them becomes abnormal or non-functi

Author: Stephen Shears
Publisher: Oxford University Press, USA
Keywords: approach, practical, inositides, signalling
Number of Pages: 229
Published: 1997-06-15
List price: $105.00
ISBN-10: 0199636389
ISBN-13: 9780199636389

Inositide research has infiltrated numerous branches of biochemistry, physiology, and molecular biology. Consequently, methodological information has been scattered far and wide. This book unites a wide selection of the most fundamental and commonly used techniques. Contributors come from international signal transduction laboratories that have been actively involved in developing and refining these techniques. A unique feature of the book is a catalog of non-commercial sources of synthetic inositide analogues. Because there’s an emphasis on broader applications instead of the more eso

Author: I. Fairweather
Publisher: Springer
Keywords: metazoa, lower, prokaryotes, signalling, cell
Number of Pages: 412
Published: 2003-12-31
List price: $225.00
ISBN-10: 1402017391
ISBN-13: 9781402017391

Cell signalling lies at the heart of many biological processes and currently is the focus of intense research interest. In multicellular organisms, it is central to how different types of cell communicate with each other and how they detect and respond to extracellular signals. Intercellular communication is vital to single-celled organisms as well, allowing them to respond to environmental cues and signals. To date, much of the understanding of signalling mechanisms has come from research on specific cell types (eg mouse lymphocyte and cardiomyocyte) or on organisms in which communi

Author: John Nelson
Publisher: Wiley
Keywords: signalling, cell, function, structure
Number of Pages: 410
Published: 2008-08-25
List price: $79.95
ISBN-10: 0470025514
ISBN-13: 9780470025512

"This book contains extremely detailed and informative content on structure and function of ligands, receptors, and signalling intermediates plus interactions … the extent of detail and appropriate referencing is impressive." –Microbiology Today, July 2009 "A very well-written book suitable for use as a reference or textbook for an undergraduate subject in cell signalling. For researchers interested in the molecular basis of cell signalling and how aberrant regulation of cell signalling proteins causes diseases, this is an excellent resource of biochemical and structural information