Authors:Uwe Lendeckel, Nigel M. Hooper,
Publisher: Springer
Keywords: proteases, biology, disease, therapy, protease, antiviral, viral, inhibitor
Number of Pages: 370
Published: 2009-08-27
List price: $189.00
ISBN-10: 904812347X
ISBN-13: 9789048123476

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegal

Authors:Nigel M. Hooper, Nigel M. Hooper, Uwe Lendeckel,
Publisher: Springer
Keywords: proteases, disease, biology, clips, intramembrane, cleaving
Number of Pages: 142
Published: 2007-09-10
List price: $169.00
ISBN-10: 1402063105
ISBN-13: 9781402063107

In recent years a growing number of proteases have been identified that catalyse peptide bond hydrolysis in the plane of the cellular membrane. These so-called intramembrane-cleaving proteases (I-CLiPs) are involved in a diverse range of cellular processes, including cell regulation, signalling, quorum sensing, protein processing, lipid metabolism and the unfolded protein response. Some I-CLiPs play critical roles in diseases such as Alzheimer s and viral infection. The authors, who are all world leaders in this exciting field of cell biology, provide an overview of the various proteases inc

Authors:John N. Abelson, Melvin I. Simon, Lawrence C. Kuo, Ju
Publisher: Academic Press
Keywords: enzymology, methods, volume, proteases, retroviral
Number of Pages: 432
Published: 1994-10-06
List price: $182.00
ISBN-10: 0121821420
ISBN-13: 9780121821425

Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Authors:Able Lajtha, Allen Honeyman, Lynda J. Katz, Mauro Ben
Publisher: Springer
Keywords: diseases, neurodegenerative, pathophysiology, proteases, role
Number of Pages: 302
Published: 2001-07-31
List price: $119.00
ISBN-10: 0306465795
ISBN-13: 9780306465796

This book looks at the role of proteases, which are enzymes that digest proteins, and the various roles that proteases play in the development of neurodegenerative diseases such as Alzheimer’s disease, ALS, epilepsy, multiple sclerosis, as well as numerous other neuromuscular diseases.

Authors:Stanley Zucker, Wen-Tien Chen,
Publisher: Academic Press
Keywords: topics, developmental, biology, current, volume, surface, proteases, cell
Number of Pages: 452
Published: 2003-04-16
List price: $192.00
ISBN-10: 0121531546
ISBN-13: 9780121531546

Cell Surface Proteases provides a comprehensive overview of these important enzymes that catalyze the hydrolysis of a protein as it degrades to a simpler substance. In the 1990s, an explosion of new discoveries shed light on the role of cell surface proteases and extended it beyond degradation of extracellular matrix components to include its influence on growth factors, cell signaling, and other cellular events. This volume unites the scientific literature from across disciplines and teases out unified themes of interactions between cell surface proteases and interconnecting cell surface-rela

Author: Caughey
Publisher: CRC Press
Keywords: immunology, clinical, allergy, biology, mast, proteases, cell
Number of Pages: 351
Published: 1995-01-15
List price: $247.95
ISBN-10: 0824794842
ISBN-13: 9780824794842

This state-of-the-art reference provides timely and clinically and experimentally useful information on the major proteins of mast cell secretory granules that are released into the lung, skin, gut, eye, and other tissues under the influence of diverse stimuli-including cytokines, growth factors, neuropeptides, and allergen-bound immunoglobulin E. Demonstrates the important roles proteases play in the maintenance of tissue homeostasis as well as in the damaging events linked with allergy and other varieties of inflammation!

Author: Abu Baker SallehRaja Noor Zaliha Raja Abdul Rahma
Publisher: Nova Science Pub Inc
Keywords: proteases, lipases, new
Number of Pages: 159
Published: 2006-09-30
List price: $120.00
ISBN-10: 1600210686
ISBN-13: 9781600210686

Enzymatic processing of lipids and oils is becoming an important area of research. Hydrolytic enzymes, such as lipases and proteases are being sought after as the biocatalysts of the future. Synthetic reactions to create new compounds that have novel properties may be achieved through biocatalysis. Some of these compounds can improve or even replace on existing products that were produced by inorganic catalysis or being fractionated from un-renewable resources, such as petroleum. The authors focused on lipases and proteases as the most critical enzymes. Proteases are already widely used in ind