Author: David Mrazek MD
Publisher: Oxford University Press, USA
Keywords: pharmacogenomics, psychiatric
Number of Pages: 280
Published: 2010-05-28
List price: $45.00
ISBN-10: 0195367294
ISBN-13: 9780195367294

Psychiatric Pharmacogenomics is a book written to help clinicians to use pharmacogenomic testing to improve the pharmacotherapy that they provide for their patients. It is designed to teach clinicians how to order pharmacogenomic tests and interpret the results. Clinical examples are used to underscore the specific indications for pharmacogenomic testing and to clarify the clinical usefulness of identifying atypical genotypes that result in problematic responses to medication.The first section of the book begins with a basic review of molecular genetics. Additionally, the book also includes

Author: Martin M. Zdanowicz
Publisher: American Society of Health-System Pharmacists
Keywords: pharmacogenomics, concepts
Number of Pages: 350
Published: 2010-01-01
List price: $69.00
ISBN-10: 1585282340
ISBN-13: 9781585282340

The new science of pharmacogenomics aims to understand how an individual’s genetic composition affects his/her response to a specific drug or class of drugs. By studying such characteristics as drug metabolizing enzymes, drug transporter activity, and receptor sensitivity, a pharmacist is better able to prescribe the right drug the first time. If you are pharmacist, resident, or student curious about this new field, start with Concepts in Pharmacogenomics. In this practical guide, you will find an overview of the science behind pharmacogenomics, followed by detailed chapters related to i

Author: Mark A. Rothstein
Publisher: Wiley-Liss
Keywords: dimensions, clinical, ethical, social, pharmacogenomics
Number of Pages: 384
Published: 2003-01-23
List price: $99.95
ISBN-10: 0471227692
ISBN-13: 9780471227694

Through analyses of the complex underlying issues, this interdisciplinary volume frames the agenda for dealing with genetic variation and incorporating pharmacogenomics into health care. The three sections of this book, Research Issues, Clinical Issues, and Social Perspectives  address key elements integral to a comprehensive discussion of this emerging field. This groundbreaking text… • Examines new research strategies, methodologies, and ethical and social considerations of pharmacogenomics • Addresses practical considerations of anticipated changes in education, training, ov

Authors:Rongling Wu, Min Lin,
Publisher: Chapman and Hall/CRC
Keywords: crc, interdisciplinary, statistics, hall, amp, computational, pharmacogenomics, chapman, statistical
Number of Pages: 368
Published: 2008-08-08
List price: $83.95
ISBN-10: 1584888288
ISBN-13: 9781584888284

Due to the tremendous accumulation of data for genetic markers, pharmacogenomics, the study of the functions and interactions of all genes in the overall variability of drug response, is one of the hottest areas of research in biomedical science. Statistical and Computational Pharmacogenomics presents recent developments in statistical methodology with a number of detailed worked examples that outline how these methods can be applied. This comprehensive volume provides key tools needed to understand and model the genetic variation for drug response and equips statisticians with a thorough unde

Authors:Werner Kalow, Urs B. Meyer, Rachel F. Tyndale,
Publisher: Informa Healthcare
Keywords: sciences, pharmaceutical, drugs, pharmacogenomics
Number of Pages: 403
Published: 2001-05-15
List price: $199.95
ISBN-10: 0824705440
ISBN-13: 9780824705442

Univ. of Toronto, Canada. Reference summarizes the history and applications, techniques, and approaches to pharmacogenomics. Discusses new methodologies used to pinpoint genetic variants, latest techniques to achieve phenotypic interpretations, accurate disease gene identification, and more.

Author: Federico Innocenti
Publisher: Humana Press
Keywords: methods, biology, molecular, protocols, pharmacogenomics
Number of Pages: 224
Published: 2005-08-15
List price: $104.00
ISBN-10: 1588294404
ISBN-13: 9781588294401

Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with H

Authors:M. Schwab, W. P. Kaschka, E. Spina,
Publisher: S. Karger AG (Switzerland)
Keywords: psychiatry, biological, advances, pharmacogenomics
Number of Pages: 139
Published: 2010-06-30
List price: $64.00
ISBN-10: 3805594984
ISBN-13: 9783805594981

In recent years, there have been major developments in the fields of pharmacogenetics and pharmacogenomics, with the potential to make drug treatments in psychiatric medicine more effective. However, improvements in drug efficacy and tolerability, as well as finding the optimal dosage, can only be realized if in vivo mechanisms of drug action and ADME (absorption, distribution, metabolism, excretion) processes (pharmacokinetics) of psychopharmacological agents are better understood. In this volume, current progress and perspectives in pharmacogenetic testing of drug-metabolizing enzymes, drug