Author: Nawin C. Mishra
Publisher: CRC Press
Keywords: nucleases, biology, molecular
Number of Pages: 296
Published: 1995-03-06
List price: $404.95
ISBN-10: 0849376580
ISBN-13: 9780849376580

Nucleases occupy a central position in the biochemistry of DNA transactions and other metabolism of nucleic acids in all organisms. They have also proven useful in modern biological studies crucial for the development of recombinant DNA technology and reverse genetics. Nucleases assist in the identification and characterization of genes responsible for several diseases and their possible alleviation by gene therapy. Molecular Biology of Nucleases introduces the properties and biological roles of nucleases. It is the one comprehensive source for newcomers to the field.

Authors:Lynne E. Maquat, Megerditch Kiledjian,
Publisher: Academic Press
Keywords: decay, volume, methods, enzymology, mrna, analysis, turnover, eukaryotes, nucleases, pathways, rna
Number of Pages: 656
Published: 2008-12-29
List price: $182.00
ISBN-10: 0123743788
ISBN-13: 9780123743787

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. The co