Author: Maxine Gowen
Publisher: CRC Press
Keywords: metabolism, cytokines
Number of Pages: 432
Published: 1991-12-18
List price: $404.95
ISBN-10: 0849362687
ISBN-13: 9780849362682

Cytokines and Bone Metabolism presents a comprehensive review of the research done to date on the role of cytokines in bone metabolism. All of the major groups of cytokines and growth factors are covered, and more than 2,000 references are included. In each chapter, the biochemistry and wider cellular actions of individual factors are reviewed before data detailing the in vitro and in vivo actions in bone are presented. Extensive reviews of the cell biology of bone, the potential role of cytokines in bone diseases, and the theoretical and practical possibilities for pharmacological interventio

Authors:Gerald T. Keusch, Masanobu Kawakami,
Publisher: Ios Pr Inc
Keywords: gut, cholera, cytokines
Number of Pages: 376
Published: 1997-01
List price: $98.00
ISBN-10: 905199298X
ISBN-13: 9789051992984

This book covers the role of peptide mediators in the intestinal responses to infectious and inflammatory challenges presented by diverse disease states, including inflammatory bowel disease and infectious diarrheas and dysenteries, and the epidemiology and pathogenesis of cholera and related diarrheal diseases. The more than 40 papers included in the volume are written by leading researchers working on cytokines and mucosal responses. The papers are the results of interactive scientific research between investigators from the U.S. and Japan, through a group of panels focusing on the following

Author: T. A. Luger
Publisher: Informa Healthcare
Keywords: clinical, dermatology, basic, cytokines, growth, factors, epidermal
Number of Pages: 504
Published: 1993-09-02
List price: $299.95
ISBN-10: 0824791029
ISBN-13: 9780824791025

This reference enhances the understanding of skin pathophysiology by examining a selection of cytokines and growth factors that are either produced by the skin or have an influence on it.;Illustrating the importance of cytokine and growth factor interactions within the cytokine network, Epidermal Growth Factors and Cytokines: discusses a variety of cytokines, including the interferons, tumor necrosis factor, and interleukins 1, 6, 8, and 10; describes platelet-derived growth factor, fibroblast growth factors, and transforming growth factor -alpha and -beta; elucidates the skin’s cytokine

Authors:M. W. Bodmer, Brian Henderson,
Publisher: CRC-Press
Keywords: toxicology, pharmacology, cytokines, modulation, therapeutic
Number of Pages: 368
Published: 1996-03-23
List price: $169.95
ISBN-10: 0849383811
ISBN-13: 9780849383816

Cytokines are peptide or protein cell-to-cell signaling molecules that play vital roles in normal cell and tissue homeostasis, as well as in responses to infectious agents. Because of their importance in virtually all forms of pathology, the pharmaceutical industry is devoting great effort to develop methods for the control of cytokine synthesis or action.This is the first volume to bring together experts from academia and the pharmaceutical industry to discuss problems and solutions in the therapeutic control of cytokines. An introductory section reviews the biology, physiology, and pathology

Authors:Christopher P. Phelps, Elena A Korneva,
Publisher: Elsevier Science
Keywords: biology, neuroimmune, volume, brain, cytokines
Number of Pages: 608
Published: 2008-07-02
List price: $199.95
ISBN-10: 044453041X
ISBN-13: 9780444530417

This book opens a new page of neuroimmunebiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of central nervous system cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthes

Author: H. Redl
Publisher: Birkhäuser Basel
Keywords: progress, inflammation, research, shock, septic, severe, sepsis, amp, cytokines
Number of Pages: 369
Published: 2003-09-04
List price: $299.00
ISBN-10: 3764358777
ISBN-13: 9783764358778

This book deals with the central role of cytokines in the generalized inflammatory response of the host as the consequence of severe infection/endotoxin action. International specialists cover several aspects in 20 chapters starting with the agents responsible (endotoxin, superantigens) and recognition during cytokine induction. Further chapters deal with the signal transduction cascade, its modulation due to sex or genetic polymorphism, and the possibilities and problems in detection (including surrogate markers). Major targets of actions are covered in the chapters on coagulation/fibrinolys

Authors:Wim B. van den Berg, Pierre Miossec,
Publisher: Birkhäuser Basel
Keywords: inflammation, research, progress, injury, joint, cytokines
Number of Pages: 295
Published: 2004-07-12
List price: $219.00
ISBN-10: 3764370017
ISBN-13: 9783764370015

This topical insight in the role of cytokines in joint inflammation and joint destruction is important for a better understanding of key processes in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Apart from the impact of well-known and novel cytokines on joint tissues, the various chapters address the issue of targeted therapy with biological response modifiers and future interventions with carefully designed inhibitors. Special attention is given to elements of synovial cell activation, cell-cell interaction, cytokine interplay as well as mechanisms of cartilage destruct