Authors:J Vercruysse, R S Rew,
Publisher: CABI
Keywords: therapy, antiparasitic, lactones, macrocyclic
Number of Pages: 464
Published: 2002-12
List price: $200.00
ISBN-10: 0851996175
ISBN-13: 9780851996172

Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations. There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.

Authors:N. Anand, S. Sharma?,
Publisher: Elsevier Science
Keywords: pharmacochemistry, library, drugs, antiparasitic, design, synthesis, approaches
Number of Pages: 524
Published: 1997-07-24
List price: $293.00
ISBN-10: 0444894764
ISBN-13: 9780444894762

This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the ’biochemical targets’ available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinic

Author: Paul M. Selzer
Publisher: Wiley-VCH
Keywords: drug, discovery, infectious, candidates, diseases, molecular, antibacterial, antiparasitic, targets
Number of Pages: 509
Published: 2009-06-29
List price: $210.00
ISBN-10: 3527323279
ISBN-13: 9783527323272

“… an interesting book that leads the reader through what factors can influence drug discovery and then gives specific examples on the current situation in development of drugs for particular parasitic and bacterial diseases.” –ChemMedChem, 2009 Addressing parasitic diseases and those caused by bacteria, this much needed reference and handbook provides a unique insight into the approach adopted by commercial science towards infectious diseases, including the work of medicinal chemists. Many of the authors are scientists with hands-on experience of drug discovery units within the