Author: Sean Ekins
Publisher: Wiley-Interscience
Keywords: pharmaceutical, wiley, series, technologies, industry, chemicals, environmental, toxicology, risk, assessment, computational
Number of Pages: 830
Published: 2007-06-29
List price: $169.00
ISBN-10: 0470049626
ISBN-13: 9780470049624

A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicalsThis unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk ass

Authors:Sean Ekins, Jinghai J. Xu,
Publisher: Wiley
Keywords: technologies, tools, wiley, pharmaceutical, industry, series, emerging, efficacy, safety, biologics, discovery, drug
Number of Pages: 424
Published: 2009-01-14
List price: $115.00
ISBN-10: 0470225556
ISBN-13: 9780470225554

Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug dis

Authors:Sean Ekins, Binghe Wang,
Publisher: Wiley-Interscience
Keywords: development, series, drug, discovery, wiley, computer, pharmaceutical, research, applications
Number of Pages: 817
Published: 2006-06-30
List price: $155.00
ISBN-10: 0471737798
ISBN-13: 9780471737797

A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a uni

Author: Paul Ekins
Publisher: Routledge
Keywords: growth, prospects, sustainability, environmental, economic
Number of Pages: 392
Published: 1999-12-22
List price: $220.00
ISBN-10: 0415173329
ISBN-13: 9780415173322

Paul Ekins breaks new ground in defining the conditions of compatibility between economic growth and environmental sustainability, an provides measures and criteria by which the environmental sustainability of economic growth, as it occurs in the real world, may be judged. It is argued that "green growth" is not only theoretically possible but economically achievable and the author shows what environmental and economic policies are required to achieve this.

Authors:Paul Ekins, Tancrede Voituriez,
Publisher: Earthscan Publications Ltd.
Keywords: critical, methods, outcomes, assessment, impact, globalization, sustainability, trade
Number of Pages: 256
Published: 2009-06-01
List price: $79.95
ISBN-10: 184407661X
ISBN-13: 9781844076611

Trade liberalization, as promoted by the World Trade Organization (WTO) has become one of the dominant drivers and most controversial aspects of globalization. Trade sustainability impact assessments (SIAs) were introduced as a means of generating better understanding of the social and environmental impacts of trade liberalization and of making those impacts more consistent with sustainable development. This book takes a hard look at the practice of Trade SIAs to date, and the extent to which they have achieved their objectives and improved the outcomes of trade negotiations. It proposes sever

Authors:Richard Ekins, David King,
Publisher: Routledge
Keywords: dressing, sex, changing, cross, aspects, genders, social, blending
Number of Pages: 288
Published: 1995-12-20
List price: $190.00
ISBN-10: 0415115515
ISBN-13: 9780415115513

Considers the treatment of gender blenders by the medical framework, in literature, the press and telephone sex lines and examines its prominence in recent contemporary cultural and queer theory.

Authors:Richard Ekins, David King,
Publisher: Routledge
Keywords: dressing, sex, changing, cross, aspects, genders, social, blending
Number of Pages: 288
Published: 1995-12-20
List price: $53.95
ISBN-10: 0415115523
ISBN-13: 9780415115520

Blending Genders is concerned with those who attempt to or succeed in blending various aspects of gender. The book describes personal experiences of cross-dressers and their social organization--in both "outsider" and "respectable" communities. The contributors consider the medical framework through which gender blending is so often seen and examine the treatment afforded gender blending in literature, the press and telephone sex lines. The book concludes with a discussion of the lively debates that have taken place concerning the politics of transgenderism in recent years and recent contribu