Author: S.R. Pandi-PerumalS.R. Pandi-Perumal; Daniel P. C
Publisher: Springer
Keywords: sleep, neuroimmunology
Number of Pages: 368
Published: 2007-04-30
List price: $149.00
ISBN-10: 0387691448
ISBN-13: 9780387691442

During the last few decades, sleep medicine and science, and many of their diverse aspects, have emerged as areas of intense medical and scientific interest. Of these, sleep and neuroimmunology, which cut across many behavioral states, are highly interlinked, inherently fascinating and touching upon many facets of human health and well-being. Elucidating the roles of immune substances and cells in central nervous system functions, especially their involvement in the regulation of sleep and wakefulness, may help unravel pathophysiologic mechanisms of sleep disorders and improve their management

Authors:S.R. Pandi-Perumal, J.M. Monti,
Publisher: Birkhäuser Basel
Keywords: sleep, pharmacology, clinical
Number of Pages: 239
Published: 2006-04-03
List price: $189.00
ISBN-10: 3764372621
ISBN-13: 9783764372620

The field of sleep medicine is growing rapidly, and the clinical pharmacology of sleep is gaining much attention from sleep physicians. Many new drugs are in the process of being developed and tested for their possible usefulness in the treatment of sleep disorders. The opportunity for further advancement in this field is very promising. This volume covers the clinical and pharmacological treatment of several important sleep disorders such as insomnia, sleep apnea, narcolepsy, restless legs syndrome, and periodic limb movement syndrome. It further addresses the use of sleep medications in c

Authors:Daniel P. Cardinali, S. R. Pandi-Perumal,
Publisher: Springer
Keywords: wakefulness, sleep, correlates, neuroendocrine
Number of Pages: 649
Published: 2005-08-19
List price: $159.00
ISBN-10: 0387236414
ISBN-13: 9780387236414

As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management.   From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field. Anyone who regularly reads the literature on sleep, biological rhythms

Authors:S. R. Pandi-Perumal, Daniel P. Cardinali,
Publisher: Nova Science Pub Inc
Keywords: therapy, molecules, melatonin
Number of Pages: 906
Published: 2007-09-30
List price: $265.00
ISBN-10: 1600211216
ISBN-13: 9781600211218

Melatonin is a neurohormone produced in the brain by the pineal gland, from the amino acid tryptophan. The synthesis and release of melatonin are stimulated by darkness and suppressed by light, suggesting the involvement of melatonin in circadian rhythm and regulation of diverse body functions. Levels of melatonin start to increase prior to bedtime. Synthetic melatonin supplements have been used for a variety of medical conditions, most notably for disorders related to sleep. Melatonin possesses antioxidant activity, and many of its proposed therapeutic or preventive uses are based on this pro

Authors:Jaime Monti, S. R. Pandi-Perumal, Christopher M. Sin
Publisher: Cambridge University Press
Keywords: wakefulness, sleep, neurochemistry
Number of Pages: 506
Published: 2008-02-18
List price: $132.00
ISBN-10: 0521864410
ISBN-13: 9780521864411

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internatio

Authors:Joris C. Verster, S. R. Pandi-Perumal, Jan G. Ramaek
Publisher: Birkhäuser Basel
Keywords: safety, traffic, driving, drugs
Number of Pages: 559
Published: 2008-12-18
List price: $219.00
ISBN-10: 3764399228
ISBN-13: 9783764399221

Drugs, Driving and Traffic Safety gives a comprehensive overview of the effects of different medical conditions like neurological disorders, anxiety and depression and their pharmaceutical treatment on driving ability. In addition, the effects of alcohol and drugs of abuse are discussed. Leading experts present the different methodologies to examine effects of drugs on driving, and summarize the recent scientific evidence including epidemiological studies, roadside surveys, laboratory tests, driving simulators, and the standardized driving test. The volume includes guidelines of the Internati

Authors:Joris C. Verster,  S.R. Pandi-Perumal, David S
Publisher: Humana Pre
Keywords: medicine, clinical, life, quality, sleep
Number of Pages: 534
Published: 2008-03-21
List price: $209.00
ISBN-10: 1603273409
ISBN-13: 9781603273404

The first of its kind, Sleep and Quality of Life in Clinical Medicine provides an evidence-based introduction to the interface between sleep wide range of medical disorders. Many patients experience sleep disturbances secondary to their primary illness and this often has a negative effect on their quality of life. Sleep and Quality of Life in Clinical Medicine is essential reading for all health care professionals concerned with their patients well being. A clinically focused, comprehensive review for physicians and other health providers, this volume is a state-of-the-art reference work that