Author: Mohamed Al-RubeaiMohamed Al-Rubeai;Martin Fussene
Publisher: Springer
Keywords: engineering, cell, biology, systems
Number of Pages: 433
Published: 2007-01-19
List price: $239.00
ISBN-10: 1402052510
ISBN-13: 9781402052514

A comprehensive guide to the revolutionary area of systems biology and its application in cell culture engineering, this volume presents an overall picture of the current topics central to structural and functional genomics, proteomics, metabolomics and bioinformatics, including such hot topics as RNAi, metabolic engineering and unfolded protein response. It includes reviews of the cellular response of environmental modulation such as low temperature and osmolarity, critical assessments of the applications of metablomics and fluxomics approaches, examination of the utility of modulation of key

Author: Mohamed Al-Rubeai
Publisher: Springer
Keywords: engineering, cell
Number of Pages: 250
Published: 1999-06-30
List price: $183.00
ISBN-10: 0792357906
ISBN-13: 9780792357902

Integrating advances in molecular biology into bioprocesses presents a continuous challenge to scientists and bioengineers. This series is conceived to help meet this challenge. It examines and assesses the feasibility of new approaches for the modification of cellular function such as gene expression, protein processing, secretion, glycosylation, immortalisation, proliferation, and apoptosis as well as the systematic study of the metabolic genotype--phenotype relationship. The series provides detailed coverage of the methodology for improving cellular properties of cells used in the

Author: Mohamed Al-Rubeai
Publisher: Springer
Keywords: cell, engineering, line, development
Number of Pages: 253
Published: 2009-09-09
List price: $189.00
ISBN-10: 9048122449
ISBN-13: 9789048122448

Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology invol

Authors:Julian Chaudhuri, Mohamed Al-Rubeai,
Publisher: Springer
Keywords: design, operation, principles, engineering, tissue, bioreactors
Number of Pages: 375
Published: 2005-11-28
List price: $219.00
ISBN-10: 1402037406
ISBN-13: 9781402037405

Developments in tissue engineering for human medicine are increasing rapidly. Advances in stem cell biology, biomaterials science and scaffold design underpin this emerging science. An equally important facet of this field is the rational design and operation of bioreactors to control the nascent tissue growth. For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for se

Authors:Mohamed Al-Rubeai, Martin Fussenegger,
Publisher: Springer
Keywords: apoptosis, engineering, cell
Number of Pages: 344
Published: 2004-08-03
List price: $219.00
ISBN-10: 1402022166
ISBN-13: 9781402022166

The series Cell Engineering is the first and only major reference work on the development of cellular systems for the production of recombinant glycoproteins, gene and cell therapies, drug screening and tissue engineering. This volume on "Apoptosis" is intended to review the state-of-the-art with in-depth assessments of this type of programmed cell death. The aim of the volume is to make the recent developments in apoptotic research readily accessible to biologists, biotechnologists and cellular engineers. The implication of apoptosis in the suppression of diseases and prolonging survival of c

Author: Mohammed Al-Rubeai
Publisher: Springer
Keywords: glycosylation, engineering, cell
Number of Pages: 244
Published: 2002-06-30
List price: $169.00
ISBN-10: 1402007337
ISBN-13: 9781402007330

Univ. of Birmingham, UK. Text provides reviews of the advances in glycans and recombinant proteins. Contains an in-depth assessment of methodology and various approaches for the improvement of glycoprotein production. Written for research students, scientists, industrial biotechnologists, and biochemical engineers. Expanded-outline format.

Author: Mohamed Mohamed El-Wakil
Publisher: Amer Nuclear Society
Keywords: transport, heat, nuclear
Number of Pages: 502
Published: 1981-06-01
List price: unknow
ISBN-10: 0894480146
ISBN-13: 9780894480140